Risperdal?
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I'm am Major Depressive and have tried all the anti-depressants under psychiatric treatment - none seem to work. I've been on Xanax for nearly three years (1 mg every evening) - it doesn't help, but I am so hooked on it that I don't want to give it up. I have the opportunity to obtain Risperdal from a "reliable source" without prescription - can anyone tell me if it helps and what it does to you? I'd appreciate any help before I send off for it.
Answer:
Risperdal is supposed to be for schizophrenia but it is said that it can also help depression sometimes. It's worth a shot if nothing else's worked. In most cases it doesn't have all the terrible side effects the older antipsychotics had. You might think about trying Zyprexa(olanzapine) instead if you can get a hold of it. It's sort of the same type of drug used for schizophrenia and can help with depression too, but it has a little bit less of a chance of giving you tardive dyskenisia, that disorder where you can start getting tics on any part of your body and can sometimes become permanent. I don't want to alarm you, the chances are very very low with Risperdal, it's not like the old antipsychotics that had a very high chance of giving you this. I don't know the exact percentages but I think it might be something like less than 5% chance for Risperdal as opposed to the 40 or 50% chance with the older antipsychotics, and for Zyprexa it might be 3% or something like that. I would rather go with the one that had the absolute least chance, but Risperdal's fine too if you just wanna try that. Another thing is that it almost always takes a year or more of taking an antipsychotic for you to develop tardive dyskenisia, so knowing this and that the chances are very very low of developing this side effect, you shouldn't be afraid of starting it. It's much lower. These are the probabilities of developing *any* "extrapyramidal" (movement-related) side effect (EPS), not just tardive dyskinesia. The rate of TD goes up the longer you take a drug; with the older antipsychotics, such as Thorazine, it's about 5% after 1 year, 10% after 2 years, 15 after 3 years, and 19 after 4 years. The incidence with both Zyprexa and Risperdal is extremely low; I don't know if I've ever heard of a case with either of these (there may have been a handful). Other EPS include akathisia (extreme restlessness), tremor, dystonias (muscular spasms), rigidity, and shuffling gait. Probably about half of all the people taking the older antipsychotics experience some form of EPS. The rate is around 25% with both Risperdal and Zyprexa. Also, EPS are related to the dose you take, and lower doses are required for depression than for psychotic disorders. For example, the rate of EPS for people taking 5mg of Zyprexa or 2mg of Risperdal is about 15%. The symptoms are also less severe at lower doses. I took Risperdal for two months this past year and it basically wiped out my emotions. I felt very little of anything let alone side effects. I started taking Nortriptyline with minor improvement (The SSRI's never worked for me) and then we added Zyprexa and it was a world of difference. After 25 years of depression and dozens of meds I think Zyprexa has done more for me than anything I've tried so far.
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