Does Desipramine Cause Weight Gain??(was Re: Desipramine And Effexor (was Re: Wellbutrin)
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I have tried most a.d.'s, most recently Effexor XR, w/ Klonipin, and it SUCKS..it makes me tired AND anxious at the same time.(Plus..sexual side effects, constipation, etc.) Anyways, am considering going back to trying a trycyclic. One thing, out of all side effects, I WILL NOT TOLLERATE, though, is weight gain. Now, I found that the Brand Name version of Nortryptiline (Pamelor), helped me lose alot of weight, but caused one problem I seem to have with most a.d.s....throat, sinus, and ear infections.(quite common with many a.d.'s, from what I've read.). Pamelor also seemd to have an on/off a.d effect with me....sometimes it would work...often it didn't. So, could you Desipramine users please post ANY or ALL side effects, usefullness, etc. I think many SSRI non-responders might benefit from this too.
Answer:
My wonderful desipramine side effects (and workarounds): 1. constipation (lots of fiber 1 cereal) 2. increased appetite (i needed to gain weight anyway) 3. blurred vision (not too bad) 4. blackouts when getting up too fast (not as much anymore, crouch down though when it happens) 5. sweating (run the fan at work) 6. hair loss? not sure if this is real, or if its caused by something else. This too can happen: I was on desipramine for 8 years 300mg./day and I experienced no serious side effects. A little problem sometimes with urinary retention and orthosttatic hypertension, but it was genuinely trivial. Weight gain? Hit the gym and put the weight where it belongs, in arms and not around heart for example.
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