No Med Seems To Work - Help!
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I've tried many different AD's and none of them seems to work. I've tried Prozac, twice, the second time at 40 mg/day; Elavil; Buspar (anti-anxiety drug); a couple of tri-cyclics which gave me too many side effects (Imiprimane and Desipramine [sp?]); Trazodone; and St. John's Wort. I've tried each of these for a good amount of time, 2 or more months, except the side-effect ones, which I stopped after a few days because of the side effects.
Answer:
I have found that 5 or 6 300 mg standard capsules morning and evening is what I need. That is 3600 mg per day. I have no side effects from that dosage. I also found that some brands just don't work. (the Pharmasave house brand, in particular) I use Webber (it's the cheapest and comes bundled with gincko or a stress herb) If you wish to try larger doses you should build up over two or three days at least. I think it would be safe to go as far as 6000 mg per day if necessary, from what I have read, although I have never needed to go that high. It's unfortunate, but, at the current state of the art, there's no way to predict the likely success or failure of meds on any one individual nor, for sure, which one, if any, will work. There's a lot more success with 'which one' than 'whether any'. There's considerable research ongoing in both, and other areas, of dealing with clinical depression. While there are meds you've not tried and combinations thereof, it's understandable that you'd be reluctant to spend more money in this way. Somewhere between 20% and 25% of depressives don't respond to the current antidepressants at all. Often those who want to give up on a particular antidepressant because of some side effects, if persuaded to stick it out, find the side effects diminish and the drug take effect properly. Of those depressives refractory to medication, about half respond positively to ECT. Sounds to me that you are playing Russin Rolette. If you had Diabetis, would you go off your insulin for a month every year? Biocemical depression, is a medical condition. The medication change the chemicals in you brain. You only fall deeper each time you start to treat yourself instead of following your pdoc's advice.
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